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Deep tech VC fund The Engine raises $230M for its second fund from MIT and new backer Harvard

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Deep tech. Hard tech. Or, as The Engine dubs it, Tough Tech.

Venture investing today is essentially identical to what happens on Wall Street, focused on data rooms, spreadsheets, SaaS churn models and cohort analysis. Yet, the history of venture capital firms is heavily interwoven with universities and their research. Some of the most famous VC funds like Kleiner Perkins got their start funding compelling research projects out of laboratories and financing their commercialization toward scale.

Technical risk is something many VCs like to avoid, but The Engine has built an entire brand and thesis around it. Centered around Kendall Square and the broader MIT ecosystem, The Engine debuted a couple of years ago with a focus on “tough tech” problems that are perhaps a touch too early for other VCs. That’s led to investments in companies like Boston Metal, which builds environmentally-friendly steel alloys, WoHo, which is rethinking modular building construction that we profiled last week, and Commonwealth Fusion Systems, which is developing fusion power.

Indeed, the firm’s portfolio page has to be one of the most interesting in the industry today.

The good news is that the firm’s ambitious funding strategy looks set to continue. It announced this morning that it has raised $230 million toward the firm’s second fund, which on top of the firm’s first fund brings it to a total of $435 million under management. In a press statement, the firm said that it has funded 27 portfolio companies out of its first fund. While MIT continues to be the anchor LP, Harvard joined for Fund 2, creating a cross-Cambridge, MA venture platform.

Katie Rae remains CEO and managing partner of the fund, and her team has expanded over the past few years as the firm has scaled up.

One interesting point that we haven’t noted previously is that MIT is building The Engine a 200,000 square foot building near its campus that will offer massive space for startups and portfolio companies to start and grow over time. That building is expected to open in 2022, hopefully when this whole pandemic situation allows for in-office collaboration again.

Boston has become something of a hub for deeper technical projects. Local startup Desktop Metal, which builds 3D printers that can print metal, is going through a SPAC process that values the company at roughly $2.5 billion. With this latest news from The Engine, it seems clear that Boston’s tough tech ecosystem will continue to have a pipeline of interesting and compelling companies.

Lyron Foster is a Hawaii based African American Musician, Author, Actor, Blogger, Filmmaker, Philanthropist and Multinational Serial Tech Entrepreneur.

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Neuroglee gets $2.3 million to develop digital therapeutics for neurodegenerative diseases

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There are now about 50 million people with dementia globally, a number the World Health Organization expects to triple by 2050. Alzheimer’s is the leading cause of dementia and caregivers are often overwhelmed, without enough support.

Neuroglee, a Singapore-based health tech startup, wants to help with a digital therapeutic platform created to treat patients in the early stages of the disease. Founded this year to focus on neurodegenerative diseases, Neuroglee announced today it has raised $2.3 million in pre-seed funding.

The round was led by Eisai Co., one of Japan’s largest pharmaceutical companies, and Kuldeep Singh Rajput, the founder and chief executive officer of predictive healthcare startup Biofourmis.

Neuroglee’s prescription digital therapy software for Alzheimer’s, called NG-001, is its main product. The company plans to start clinical trials next year. NG-001 is meant to complement medication and other treatments, and once it is prescribed by a clinician, patients can access its cognitive exercises and tasks through a tablet.

Neuroglee founder and CEO Aniket Singh Rajput (brother of Kuldeep) told TechCrunch that its first target markets for NG-001 are the United States and Singapore, followed by Japan. NG-001 needs to gain regulatory approval in each country, and it will start by seeking U.S. Food and Drug Administration clearance.

Once it launches, clinicians will have two ways to prescribe NG-001, through their healthcare provider platform or an electronic prescription tool. A platform called Neuroglee Connect will give clinicians, caregivers and patients access to support and features for reimbursement and coverage.

The software tracks patients’ progress, such as the speed of their fingers and the time it takes to complete an exercise, and delivers personalized treatment programs. It also has features to address the mental health of patients, including one that shows images that can bring up positive memories, which in turn can help alleviate depression and anxiety when used in tandem with other cognitive behavioral therapy techniques.

For caregivers and clinicians, NG-001 helps them track patient progress and their compliance with other treatments, like medications. This means that healthcare providers can work closely with patients even remotely, which is especially important during the COVID-19 pandemic.

 

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Govtech intelligence platform, The Atlas for Cities, bought by Government Executive Media Group

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The Atlas for Cities, the 500 Startups-backed market intelligence platform connecting tech companies with state and local governments, has been acquired by the Growth Catalyst Partners-backed publishing and market intelligence company Government Executive Media Group.

The San Diego-based company will become the latest addition to a stable of publications and services that include the Route Fifty, publication for local government and the defense-oriented intelligence service, DefenseOne.

The Atlas provides peer-to-peer networks for state and local government officials to share best practices and is a marketing channel for the startups that want to sell services to those government employees. Through The Atlas, government officials can talk to each other, find case studies for best practices around tech implementations, and post questions to crowdsource ideas.

Government contractors can use the site to network with leadership and receive buyer intent data to inform their strategy in the sector, all while getting intelligence about the problems and solutions that matter to state and local jurisdictions across the nation. 

The Atlas delivers on GEMG’s promise to look for companies that complement and supplement the full suite of offerings that we provide to our partners to reach decision makers across all facets of the public sector,” said Tim Hartman, CEO of Government Executive Media Group, said in a statement.

Led by Ellory Monks and Elle Hempen, The Atlas for Cities launched in 2019 and is backed by financing from individual investors and the 500 Startups accelerator program. It now counts 21,000 government officials across 3,400 cities on its platform.

“State and local governments in the United States spend $3.7 trillion per year. That’s almost 20% of GDP,” said Elle Hempen, co-founder of The Atlas. “Our mission to increase transparency and access for local leaders has the opportunity to transform this enormous, inefficient market and enable tangible progress on the most important issues of our times.”

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Google shutting down Poly 3D content platform

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Google is almost running out of AR/VR projects to kill off.

The company announced today in an email to Poly users that they will be shutting 3D-object creation and library platform “forever” next year. The service will shut down on June 30, 2021 and users won’t be able to upload 3D models to the site on April 30, 2021.

Poly was introduced as a 3D creation tool optimized for virtual reality. Users could easily create low-poly objects with in-VR tools. The software was designed to serve as a lightweight way to create and view 3D assets that could in turn end up in games and experiences, compared to more art and sculpting-focused VR tools like Google’s Tilt Brush and Facebook’s (now Adobe’s) Medium software.

Google has already discontinued most of the company’s AR/VR plays, including most notably their Daydream mobile VR platform.

The AR/VR industry’s initial rise prompted plenty of 3D-centric startups to bet big on creating or hosting a library of digital objects. As investor enthusiasm has largely faded and tech platforms hosting AR/VR content have shuttered those products, it’s less clear where the market is for this 3D content for the time being.

Users that have uploaded objects to Poly will be able to download their data and models ahead of the shutdown.

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